How to get pregnant fast on metformin?
Gynecologists use metformin as part of the treatment to get pregnant; we tell you how:
Metformin to get pregnant
Women who have insulin resistance may have various gynecological problems, including difficulty getting pregnant. Therefore, gynecologists meditate metformin to help the female to control insulin resistance and thus maintain an adequate menstrual cycle and achieve pregnancy.
Metformin is not as such an infertility treatment, but it helps to regulate the menstrual cycle of women affected by insulin resistance and thus achieve pregnancy more easily. Also, if the woman controls her insulin resistance, she will not only become pregnant but will significantly reduce the risk of losing the baby in the following months of pregnancy.
When the woman is able to balance her hormonal status, indicates the Internist Doctor José Víctor Manuel Rincón Ponce, of the Mexican Social Security Institute, her menstrual cycles are also regularized, and thus it will be easier to generate an optimal environment for her body to have and maintain a full-term pregnancy.
Getting pregnant suffering from polycystic ovary syndrome
Polycystic ovary syndrome, a disorder characterized by irregular menses, hormonal alteration, and the appearance of multiple cysts in the ovaries, affects approximately 8% of the female population. What causes this pathology is still a doubt, and the diagnosis and treatment have been much discussed.
What is known is that this is one of the main reasons for infertility in women, to which you can add some metabolic disorders, such as obesity or insulin resistance.
A study conducted by a group of researchers from different American universities, in order to ratify the results of small studies on the best method to treat infertility in women with polycystic ovarian syndrome, and which has been published in The New magazine England Journal of Medicine, defines that the old medication used to induce ovulation through its action on the follicle-stimulating hormone, clomiphene citrate, is the best option for women who suffer from this disorder to become pregnant, it is also the simplest, cheap, safe and effective treatment.
Of more recent use was metformin, a medicine used to treat type 2 diabetes, which by improving glucose and obesity favored conception. The study was carried out with 626 infertile women due to this syndrome and distributed them into three groups, one group received the antidiabetic drug (extended-release metformin), another the ovulation inducer (clomiphene citrate) and the third received a combination of both medications. The treatment and follow-up lasted a maximum of 30 weeks or until they achieved pregnancy.
At the end of the study, women who had received clomiphene showed a birth rate three times higher than those of the metformin group; in addition, the former also had a higher number of multiple pregnancies.
Those who took a combination of both drugs showed an ovulation rate higher than the rest, but births were not fulfilled, although they matched multiple pregnancies with the group that received the ovulation inducer.
Previous studies had suggested the opposite of this, but the result was not analyzed at birth, but in the ovulation rate, which is not the desire of women suffering from this disorder.
Journal Watch More information
- Barbieri RL, et al. (2017). Metformin for treatment of the polycystic ovary syndrome.
- Commit to healthy choices to help prevent birth defects. (2017).
- Feig DS, et al. (2011). Metformin therapy during pregnancy. DOI:
- Glucophage (metformin hydrochloride) tablets; Glucophage XR (metformin hydrochloride) extended-release tablets. (2017).
- Mayo Clinic Staff. (2017). Gestational diabetes.
- Mayo Clinic Staff. (2017). Polycystic ovary syndrome (PCOS).
- PCOS: Insulin and metformin. (2016).
- Type 2. (n.d.).
- Xeng XL, et al. (2016). Effects of metformin on pregnancy outcomes in women with polycystic ovary syndrome: A meta-analysis. DOI: